52334-81-3

  • Product Name:2-Chloro-5-trifluoromethylpyridine
  • Molecular Formula:C6H3ClF3N
  • Purity:99%
  • Molecular Weight:181.545
Inquiry

Product Details

Reputable Factory Supply Hot Sale 2-Chloro-5-trifluoromethylpyridine 52334-81-3 with Cheapest Price

  • Molecular Formula:C6H3ClF3N
  • Molecular Weight:181.545
  • Appearance/Colour:white to yellowish crystalline low melting solid 
  • Melting Point:29-33 °C 
  • Boiling Point:171.636 °C at 760 mmHg 
  • PKA:-2.57±0.10(Predicted) 
  • Flash Point:57.604 °C 
  • PSA:12.89000 
  • Density:1.417 g/cm3 
  • LogP:2.75380 

2-Chloro-5-trifluoromethylpyridine(Cas 52334-81-3) Usage

Synthesis

2-Chloro-5-trifluoromethylpyridine can be synthesized by fluorination of 2-chloro-5-trichloromethylpyridine.

Chemical Properties

white to yellowish crystalline low melting solid

Uses

2-Chloro-5-(trifluoromethyl)pyridine may be employed as model substrate to investigate the regioexhaustive functionalization.

General Description

2-Chloro-5-(trifluoromethyl)pyridine is a chloro(trifluoromethyl) pyridine.

InChI:InChI=1/C6H3ClF3N/c7-5-2-1-4(3-11-5)6(8,9)10/h1-3H

52334-81-3 Relevant articles

METHOD FOR SEPARATING AND PURIFYING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE

-

Paragraph 0092-0095, (2020/02/27)

A method for separating and purifying 2-...

METHOD FOR PREPARING 2,3-DICHLORO-5-TRIFLUOROMETHYLPYRIDINE WITH HIGH SELECTIVITY

-

Paragraph 0179-0216, (2020/04/24)

The present invention discloses a method...

Catalyst-Free N-Deoxygenation by Photoexcitation of Hantzsch Ester

Cardinale, Luana,Jacobi Von Wangelin, Axel,Konev, Mikhail O.

supporting information, (2020/02/15)

A mild and operationally simple protocol...

Production method of high-purity 2-chloro-5-trifluoromethylpyridine

-

Paragraph 0028-0029, (2018/03/23)

The invention provides a production meth...

52334-81-3 Process route

3-Methylpyridine
108-99-6

3-Methylpyridine

2,6-dichloro-3-(trifluoromethyl)pyridine
55304-75-1

2,6-dichloro-3-(trifluoromethyl)pyridine

2-chloro-5-trifluoromethylpyridine
52334-81-3

2-chloro-5-trifluoromethylpyridine

2-chloro-3-trifluoromethyl-pyridine
65753-47-1

2-chloro-3-trifluoromethyl-pyridine

Conditions
Conditions Yield
With hydrogen fluoride; chlorine; at 200 - 400 ℃; for 30h; Large scale;
3.7 %Chromat.
14.5 %Chromat.
47.7 %Chromat.
2-chloro-5-(Trichloromethyl)-pyridine
69045-78-9

2-chloro-5-(Trichloromethyl)-pyridine

2-chloro-5-trifluoromethylpyridine
52334-81-3

2-chloro-5-trifluoromethylpyridine

Conditions
Conditions Yield
With hydrogen fluoride; mercury(II) oxide;
87%
With antimony(III) fluoride; for 0.166667h; Heating;
54.5%
With hydrogen fluoride;
 
With hydrogen fluoride; at 130 ℃; Temperature;
 

52334-81-3 Upstream products

  • 69045-79-0
    69045-79-0

    2-choro-5-iodopyridine

  • 2923-18-4
    2923-18-4

    sodium 2,2,2-trifluoroacetate

  • 69045-78-9
    69045-78-9

    2-chloro-5-(Trichloromethyl)-pyridine

  • 5326-23-8
    5326-23-8

    6-Chloro-3-pyridinecarboxylic acid

52334-81-3 Downstream products

  • 131136-84-0
    131136-84-0

    1,4-Bis(3'-(trifluoromethyl)-6'-pyridyl)piperazine

  • 136539-99-6
    136539-99-6

    N,N-dimethyl-5-(trifluoromethyl)pyridine-2-amine

  • 136539-95-2
    136539-95-2

    Ethyl-methyl-(5-trifluoromethyl-pyridin-2-yl)-amine

  • 136539-97-4
    136539-97-4

    Isopropyl-methyl-(5-trifluoromethyl-pyridin-2-yl)-amine

Relevant Products