220000-87-3
- Product Name：4-Chloro-N-methylpicolinamide
- Molecular Formula：C7H7ClN2O
- Purity：99%
- Molecular Weight：170.598
Product Details
Reputable Factory Supply Wholesale 4-Chloro-N-methylpicolinamide 220000-87-3 with the Best Price
- Molecular Formula:C7H7ClN2O
- Molecular Weight:170.598
- Appearance/Colour:pale-yellow solid
- Vapor Pressure:0mmHg at 25°C
- Melting Point:41-43 °C
- Refractive Index:1.575
- Boiling Point:317.8 °C at 760 mmHg
- PKA:13.41±0.46(Predicted)
- Flash Point:146 °C
- PSA：41.99000
- Density:1.264 g/cm3
- LogP:1.48550
N-Methyl-4-chloropyridine-2-carboxamide(Cas 220000-87-3) Usage
|
Chemical Properties |
Pale-Yellow Solid |
|
Uses |
4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis. |
InChI:InChI=1/C7H7ClN2O/c8-5-1-2-10-6(3-5)4-7(9)11/h1-3H,4H2,(H2,9,11)
220000-87-3 Relevant articles
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, p. 777 - 781 (2002)
Urea 3 (BAY 43-9006), a potent Raf kinas...
Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-RafV600E and C-Raf kinase inhibitory activities
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A new series of benzothiazole amide and ...
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220000-87-3 Process route
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- 24484-93-3
4-Chloro-pyridine-2-carboxylic acid methyl ester
-
- 74-89-5
methylamine
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- 220000-87-3
4-chloro-N-methylpicolinamide
| Conditions | Yield |
|---|---|
|
With magnesium chloride; In tetrahydrofuran; at 20 ℃; for 2.25h;
|
98.5% |
|
In methanol; at 0 - 5 ℃; for 2h;
|
98% |
|
magnesium chloride; In tetrahydrofuran; at 20 ℃; for 2.25h;
|
98.5% |
|
With magnesium chloride; In tetrahydrofuran; at 20 ℃; for 2.25h;
|
98.5% |
|
In methanol; at 0 ℃; for 3h;
|
96% |
|
In tetrahydrofuran; methanol; at 2 - 20 ℃; for 3h;
|
94.5% |
|
In methanol; at 0 - 5 ℃; for 4h;
|
94.5% |
|
In methanol; at 0 - 5 ℃; for 2h;
|
90% |
|
In methanol; at 0 - 5 ℃; for 2h;
|
90% |
|
In water; at 20 ℃; for 3h; Solvent;
|
87% |
|
In tetrahydrofuran; methanol; at 0 ℃; for 3h;
|
84% |
|
With magnesium chloride; In tetrahydrofuran; at 20 ℃; for 16.4167h;
|
81% |
|
In methanol; at 50 ℃; for 5h;
|
59% |
|
In methanol;
|
|
|
In tetrahydrofuran;
|
|
|
In tetrahydrofuran;
|
|
|
at 20 ℃; for 3h;
|
|
|
In tetrahydrofuran; water; at 20 ℃; for 3h;
|
-
- 176977-85-8
methyl 4-chloropyridine-2-carboxylate hydrochloride
-
- 220000-87-3
4-chloro-N-methylpicolinamide
| Conditions | Yield |
|---|---|
|
With methylamine; In tetrahydrofuran; methanol; ethyl acetate;
|
97% |
|
With methylamine; In tetrahydrofuran; methanol; ethyl acetate;
|
97% |
|
With methylamine; In tetrahydrofuran; methanol; ethyl acetate;
|
97% |
|
With methylamine; In tetrahydrofuran; methanol; ethyl acetate;
|
97% |
|
With methylamine; In tetrahydrofuran; methanol; at 0 - 3 ℃; for 4h;
|
220000-87-3 Upstream products
-
53750-66-6
4-chloro-pyridine-2-carbonyl chloride
-
24484-93-3
4-Chloro-pyridine-2-carboxylic acid methyl ester
-
74-89-5
methylamine
-
626-61-9
4-Chloropyridine
220000-87-3 Downstream products
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953770-85-9
N-methyl-4-((2-(methylthio)benzo[d]thiazol-6-yl)oxy)picolinamide
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284462-74-4
4-(3-methyl-4-aminophenoxy)-N-methyl-2-pyridinecarboxamide
-
952490-55-0
4-(3,4-dinitro-phenoxy)-pyridine-2-carboxylic acid methyl amide
-
952490-92-5
4-(4-(benzyloxy)-3-chlorophenoxy)-pyridine-2-carboxylic acid methylamide
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