65753-47-1

  • Product Name:2-Chloro-3-(trifluoromethyl)pyridine
  • Molecular Formula:C6H3ClF3N
  • Purity:99%
  • Molecular Weight:181.545
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Product Details

Factory Supply Buy Quality 2-Chloro-3-(trifluoromethyl)pyridine 65753-47-1 with Reasonable Price

  • Molecular Formula:C6H3ClF3N
  • Molecular Weight:181.545
  • Appearance/Colour:semi-transparent crystals 
  • Vapor Pressure:1.188mmHg at 25°C 
  • Melting Point:36-40 °C(lit.) 
  • Refractive Index:1.447 
  • Boiling Point:171.6 °C at 760 mmHg 
  • PKA:-1.68±0.10(Predicted) 
  • Flash Point:57.6 °C 
  • PSA:12.89000 
  • Density:1.416 g/cm3 
  • LogP:2.75380 

2-Chloro-3-(trifluoromethyl)pyridine(Cas 65753-47-1) Usage

Uses

2-Chloro-3-(trifluoromethyl)pyridine may be used in the preparation of 5,5′-bis(trifluoromethyl)-2,2′-bipyridine, via modified Ullmann reaction.

General Description

2-Chloro-3-(trifluoromethyl)pyridine is a trifluoromethyl-substituted pyridine derivative.

InChI:InChI=1/C6H3ClF3N/c7-5-3-11-2-1-4(5)6(8,9)10/h1-3H

65753-47-1 Relevant articles

Preparation method of 2-chloro-3-trifluoromethylpyridine

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Paragraph 0029-0061, (2021/01/25)

The invention discloses a preparation me...

METHOD FOR SEPARATING AND PURIFYING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE

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Paragraph 0092-0095, (2020/02/27)

A method for separating and purifying 2-...

Preparation method of non-transition metal-catalyzed 2-halogenated pyridine compound

-

Paragraph 0056-0058, (2018/10/11)

The invention provides a preparation met...

Trifluoromethylation of (hetero)aryl iodides and bromides with copper(i) chlorodifluoroacetate complexes

Lin, Xiaoxi,Li, Zhengyu,Han, Xiaoyan,Weng, Zhiqiang

, p. 75465 - 75469 (2016/08/24)

A new copper-mediated trifluoromethylati...

65753-47-1 Process route

3-Methylpyridine
108-99-6

3-Methylpyridine

2,6-dichloro-3-(trifluoromethyl)pyridine
55304-75-1

2,6-dichloro-3-(trifluoromethyl)pyridine

2-chloro-5-trifluoromethylpyridine
52334-81-3

2-chloro-5-trifluoromethylpyridine

2-chloro-3-trifluoromethyl-pyridine
65753-47-1

2-chloro-3-trifluoromethyl-pyridine

Conditions
Conditions Yield
With hydrogen fluoride; chlorine; at 200 - 400 ℃; for 30h; Large scale;
3.7 %Chromat.
14.5 %Chromat.
47.7 %Chromat.
3-(trifluoromethyl)pyridine-N-oxide
22253-72-1

3-(trifluoromethyl)pyridine-N-oxide

2-chloro-5-trifluoromethylpyridine
52334-81-3

2-chloro-5-trifluoromethylpyridine

2-chloro-3-trifluoromethyl-pyridine
65753-47-1

2-chloro-3-trifluoromethyl-pyridine

Conditions
Conditions Yield
3-(trifluoromethyl)pyridine-N-oxide; With trichlorophosphate; In 1,2-dichloro-ethane; at 105 - 125 ℃; for 7h;
With triethylamine; In 1,2-dichloro-ethane; at -30 - -20 ℃; for 3h;
50.34%
25.34%

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