82572-04-1
- Product Name：(R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
- Molecular Formula：C12H13 N . Cl H
- Purity：99%
- Molecular Weight：207.703
Product Details
Reputable Manufacturer Supply Buy High Quality (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE 82572-04-1 with Efficient Delivery
- Molecular Formula:C12H13 N . Cl H
- Molecular Weight:207.703
- Vapor Pressure:9.54E-05mmHg at 25°C
- Melting Point:253-257oC(lit.)
- Boiling Point:333.9°C at 760 mmHg
- Flash Point:155.7°C
- PSA：26.02000
- LogP:4.36180
?-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE(Cas 82572-04-1) Usage
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General Description |
-(+)-1-(1-naphthyl)ethylamine hydrochloride is a chemical compound with the molecular formula C12H13N · HCl. It is a salt form of the amine compound, 1-(1-naphthyl)ethylamine, and is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical products. It is also used as a reagent in organic chemistry for the preparation of a wide range of other compounds. The hydrochloride salt form of the compound is often more stable and easier to handle than the free base form, making it a preferred choice for many applications. Additionally, it is used as a precursor in the synthesis of various drugs, including antihistamines and antidepressants, due to its aromatic structure and amine functional group. |
InChI:InChI=1/C12H13N.ClH/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11;/h2-9H,13H2,1H3;1H/t9-;/m1./s1
82572-04-1 Relevant articles
Efficient synthesis and practical resolution of 1-(naphthalen-1-yl) ethanamine, a key intermediate for cinacalcet
Mathad, Vijayavitthal T.,Shinde, Gorakshanath B.,Ippar, Sharad S.,Niphade, Navnath C.,Panchangam, Raghavendra K.,Vankawala, Pravinchandra J.
, p. 341 - 346 (2011/04/15)
An efficient synthesis of 1-(naphthalen-...
82572-04-1 Process route
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- 1073144-62-3
(1R)-1-(naphthalen-1-yl)ethanamine (R)-mandelate
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- 82572-04-1
(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
| Conditions | Yield |
|---|---|
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(1R)-1-(naphthalen-1-yl)ethanamine (R)-mandelate; With ammonia; In water; toluene;
With hydrogenchloride; In ethyl acetate; isopropyl alcohol; at 10 - 15 ℃; pH=3 - 4;
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84% |
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- 941-98-0
1'-naphthacetophenone
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- 82572-04-1
(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
| Conditions | Yield |
|---|---|
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Multi-step reaction with 4 steps
1.1: hydroxylamine hydrochloride; sodium hydroxide / methanol; water / 20 - 35 °C / pH 6 - 6.5
2.1: ammonia; hydrogen / methanol; water / 58 - 62 °C / 2574.5 - 2942.29 Torr
3.1: ethanol / 0.75 h / 60 - 65 °C / Resolution of racemate
4.1: ammonia / water; toluene
4.2: 10 - 15 °C / pH 3 - 4
With hydroxylamine hydrochloride; ammonia; hydrogen; sodium hydroxide; In methanol; ethanol; water; toluene;
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82572-04-1 Upstream products
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941-98-0
1'-naphthacetophenone
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1073144-62-3
(1R)-1-(naphthalen-1-yl)ethanamine (R)-mandelate
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1956-40-7
1-(1-naphthalenyl)ethanone oxime
82572-04-1 Downstream products
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1005450-55-4
(R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide
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1224567-99-0
3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride
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226256-56-0
cinacalcet
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163831-65-0
benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride
Relevant Products
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(S)-(-)-1-(1-Naphthyl)ethylamineCAS：10420-89-0