779-89-5

  • Product Name:3-(Trifluoromethyl)cinnamic acid
  • Molecular Formula:C10H7F3O2
  • Purity:99%
  • Molecular Weight:216.16
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Product Details

Trustworthy Factory Supply Buy Reliable Quality 3-(Trifluoromethyl)cinnamic acid 779-89-5 with Reasonable Price

  • Molecular Formula:C10H7F3O2
  • Molecular Weight:216.16
  • Appearance/Colour:white solid 
  • Vapor Pressure:0.001mmHg at 25°C 
  • Melting Point:135-137 °C(lit.) 
  • Boiling Point:289.6 °C at 760 mmHg 
  • PKA:4.25±0.10(Predicted) 
  • Flash Point:129 °C 
  • PSA:37.30000 
  • Density:1.363 g/cm3 
  • LogP:2.80320 

3-(Trifluoromethyl)cinnamic acid(Cas 779-89-5) Usage

Chemical Properties

White Solid

Uses

Had sedative hypnotic activity in mice, showing potent inhibition of spontaneous motility.

InChI:InChI=1/C10H7F3O2/c11-10(12,13)8-3-1-2-7(6-8)4-5-9(14)15/h1-6H,(H,14,15)/p-1/b5-4+

779-89-5 Relevant articles

Dual Nickel/Ruthenium Strategy for Photoinduced Decarboxylative Cross-Coupling of α,β-Unsaturated Carboxylic Acids with Cycloketone Oxime Esters

Gao, Ang,Jiang, Run-Chuang,Liu, Chuang-Chuang,Liu, Qi-Le,Lu, Xiao-Yu,Xia, Ze-Jie

supporting information, p. 8829 - 8842 (2021/06/30)

Herein, a dual nickel/ruthenium strategy...

Metal-Free Hydropyridylation of Thioester-Activated Alkenes via Electroreductive Radical Coupling

Xu, Hehuan,Liu, Jiayu,Nie, Feiyun,Zhao, Xiaowei,Jiang, Zhiyong

, p. 16204 - 16212 (2021/10/25)

An electrochemical hydropyridylation of ...

Meta-substituted piperlongumine derivatives attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis

Gong, Zhaotang,Liu, Guoyun,Mu, Wenwen,Wang, Ziqing,Yang, Jie

, (2021/11/16)

Piperlongumine (PL) has been showed to h...

Phenanthroline functionalized polyacrylonitrile fiber with Pd(0) nanoparticles as a highly active catalyst for the Heck reaction

Xiao, Jian,Zhang, Haonan,Ejike, Anyaegbu Chima,Wang, Lu,Tao, Minli,Zhang, Wenqin

, (2021/03/03)

A series of polyacrylonitrile fibers (PA...

779-89-5 Process route

malonic acid
141-82-2

malonic acid

3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

3-(trifluoromethyl)cinnamic acid
779-89-5,67801-07-4

3-(trifluoromethyl)cinnamic acid

Conditions
Conditions Yield
With piperidine; pyridine; at 110 ℃;
89%
piperidine; In pyridine; at 110 - 115 ℃;
72%
With piperidine; In pyridine; at 80 - 90 ℃;
 
With piperidine; pyridine; at 100 ℃;
 
With piperidine; pyridine; for 3h;
 
With piperidine; pyridine; at 90 ℃; Inert atmosphere;
 
With piperidine; pyridine; for 3h; Reflux;
 
With piperidine; pyridine; Reflux;
 
With piperidine; pyridine; at 115 ℃; for 12h;
 
m-trifluoromethyl-α-bromohydrocinnamic acid
1015065-52-7

m-trifluoromethyl-α-bromohydrocinnamic acid

3-(trifluoromethyl)cinnamic acid
779-89-5,67801-07-4

3-(trifluoromethyl)cinnamic acid

Conditions
Conditions Yield
m-trifluoromethyl-α-bromohydrocinnamic acid; With sodium hydroxide; water; N-benzyl-N,N,N-triethylammonium chloride; In isopropyl alcohol; at 55 - 60 ℃; for 7h;
With hydrogenchloride; water; at 0 ℃;
 

779-89-5 Upstream products

  • 110-89-4
    110-89-4

    piperidine

  • 454-89-7
    454-89-7

    3-Trifluoromethylbenzaldehyde

  • 141-82-2
    141-82-2

    malonic acid

  • 108-24-7
    108-24-7

    acetic anhydride

779-89-5 Downstream products

  • 116577-12-9
    116577-12-9

    ethyl 3-trifluoromethylcinnamate

  • 60689-14-7
    60689-14-7

    3-(3-(trifluoromethyl)phenyl)acryloyl chloride

  • 454-89-7
    454-89-7

    3-Trifluoromethylbenzaldehyde

  • 104774-87-0
    104774-87-0

    3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine